COVID-19 antibody test performance

In an effort to support the work evaluating technologies for serology (antibody) testing, the lab has developed an interactive webapp to explore the effect of changing prevalence on the population-level performance of these tests.

Because the fraction of people in the general population who have been exposed to COVID-19 (which we call the prevalence) is still low, even antibody tests with high sensitivity and specificity may end up mis-classifying a large number of people. To address this we created an interactive web app that shows the effect of changing the prevalence (as well as the test performance) on the probability that given a positive test you actually have SARS-CoV-2 antibodies. We have included data from other antibody test evaluations as well as state and county-level prevalence values for a geographically-refined interpretation of these results.


miRNA tissue atlas

Good RNA biomarkers tend to be specifically expressed in tissues relevant to the disease under investigation. In collaboration with the van Keuren-Jensen lab at TGen, we have created a human small-RNA tissue atlas. The interactive webapp enables discovery and deeper interrogation of tissue-specific miRNAs to accelerate community efforts to develop informative non-invasive biomarkers of many different diseases.

About us

The Kitchen Laboratory specialises in computational biology, functional genomics, and non-invasive diagnostics. We apply state-of-the-art statistical/machine-learning approaches and leverage the massive power and flexibility of cloud-computing to define novel biomarkers of cardiovascular disease, type 2 diabetes, neurodegenerative diseases, and various cancers.

Contact Info

CVRC • 149 13th St Charlestown, MA 02129 • USA
(617) 643-3449